NO MORE DAGGERS IN MY THIGHS!!! I’m really excited about this albeit maybe somewhat misguided…unfortunately no more daggers means a new chemo as the Ibrance/Faslodex combo didn’t do a damn thing to stabilize this cancer.
For 3 months I was on the combination therapy of an oral chemo called Ibrance and monthly shots called Flasodex. My body and I have not had a treatment break in 12 weeks. During my week off chemo, we either had our shots and/or radiation (to help with pain). And none of the chemo helped!
Pet/Ct scan dated 04/28/2016
Osseous Structures (Bones):
There are multiple areas of lytic and sclerotic lesions consistent with metastatic disease. these involve the right scapula, multiple thoracic and lumbar vertebral bodies, and pelvis.
Abnormal fluordeoxyglucose (FDG) SUV (standard uptake value) is associated with T3 at a 4.9 SUV.
Abnormal SUV is ppresent in T6, T9, T10, and T11. the most intense is T11 with an SUV of 7.4.
There is mild SUV in L2 but marked upatek in the L3 metastasis with an SUV of 9.8. L4 has mild uptake as well.
The moderate increased uptake present with the Left Iliac metastasis an SUV of 6.6. Right Sacral SUV of 4.5 and Left Sacral metastasis withb an SUV of 9.0.
Left/periacetbular metastasis (hipsocket) has an hypermetabolic SUV of 6.2.
Chest: there is underlying consolidation within the left lower lobe. Previous SUV was 2.6 now with increased uptake at 5.1. This is morphologically unchanged however may represent recurrence.
- Significant worsening of bony metastases especially within the thoracic and lumbar spine and pelvis.
- Left Lower Lobe consolidation measuring 2.2 cm having an increased SUV of 5.1 previously 2.6.
Now The Blood Guy is doing research given nothing was mentioned about my Ischiums or my C-3 lesion (found in my brain MRI). Also, a couple of these high SUV lesions may be due to radiation (XRT). The Nuker has been consulted to check the radiation fields. and he is following up the lung spot thing. I have a lot of scar tissue in my left lower lobe from my rib removal that it’s hard to tell what’s going on. However, all in all, everything is worse and the miracle drug passed by the FDA in 2015 failed spectacularly!
On May 12th I start a new chemo combo called Carbo/Gemzar (carboplatin/gemcitabine). I am also increasing my quarterly bone treatment called Zometa to monthly again and continuing with the menopause inducing shot called Zoladex. And much like the first time I went through chemo 4 years ago, I’ll be on a light steroid.
Gemzar SE’s are:
- Flu-like symptoms such as muscle pain, fever, headache, chills, and fatigue
- Fever (within 6–12 hours of first dose)
- Nausea (mild)
- Poor appetite
- Skin rash
- Hair loss
- Mouth sores
- Difficulty sleeping
- Shortness of breath
and Carboplatin’s SE’s are:
- Low blood counts (including red blood cells, white blood cells and platelets)
- Nausea and vomiting usually occurring within 24 hours of treatment
- Taste changes
- Hair loss
- Burning sensation at the injection site
- Mouth sores
- Peripheral neuropathy
- Central neurotoxicity
- Hearing loss (ototoxicity) – loss of high pitched sounds.
- Abnormal blood liver enzymes
So even with all of this looming before me I’m still excited about NOT getting those stupid shots in my thighs! I hated those things and I had so much anxiety when it was time for them. Plus I couldn’t walk for a few days after! The Blood Guy said I’ll get to keep my hair and toenails though. However at the same time I’m pissed that nothing worked. I feel like I wasted 4 months of my life, time I do not have!
I am dissappointed about this too. The Blood Guy and I were expecting a mixed result, not significant worsening. A good or bad thing, depending on your viewpoint, is my tumor markers are FINALLY showing up. CEA, CA15.3 and CA 27.29 have all doubled. For the past 2 years we thought they were completely worthless as I have been getting chemo to fight MBC with tumor markers in the single digits. Now they are in the mid to high 40’s. This means there’s more cancer expressing these markers. It’s easier to diagnose progression but bad because there’s more cancer to diagnose.
Actually, I think it still hasn’t sunk in yet. Or I’m just so exhausted from being in treatment for 12 weeks with no break, I’m like “whatever.. .next!”
so, that’s the news. I’ll write more soon and promise I’ll try not to let so much time pass between posts. I have truly been just exhausted…. but at least I don’t have to get stabbed in my thighs anymore.